New cancer pill targets KRAS and EGFR mutations in early human trial

NCT ID NCT05163028

Summary

This early-stage study is testing a new oral medication called HBI-2376 in people with advanced solid tumors that have specific KRAS or EGFR mutations. The main goals are to find the highest safe dose of the drug and to understand how the body absorbs and processes it. The trial will enroll up to 42 adults whose cancer has progressed despite standard treatments.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • BRCR Medical Center

    Plantation, Florida, 33322, United States

  • California Cancer Associates for Research and Excellence, Inc. (cCare)

    Encinitas, California, 92024, United States

  • California Cancer Associates for Research and Excellence, Inc. (cCare)

    San Marcos, California, 92069, United States

  • City of Hope

    Duarte, California, 91010, United States

  • Gabrail Cancer Center

    Canton, Ohio, 44718, United States

  • Orlando Health, Inc.

    Orlando, Florida, 32806, United States

  • Pan American Center for Oncology Trials (PanOncology Trials)

    Rio Piedras, Puerto Rico, 00935, Puerto Rico

  • Providence Medical Foundation

    Fullerton, California, 92835, United States

  • Sarcoma Oncology

    Santa Monica, California, 90403, United States

  • Texas Oncology - Tyler

    Tyler, Texas, 75702, United States

  • UCLA Hematology/Oncology

    Santa Monica, California, 90404, United States

  • Virginia Cancer Specialists

    Fairfax, Virginia, 22031, United States

Conditions

Explore the condition pages connected to this study.