New transplant approach shows promise for rare blood disorder
NCT ID NCT02918292
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a stem cell transplant from a half-matched family donor for people with severe aplastic anemia, a condition where the bone marrow stops making enough blood cells. The goal was to see if this approach could improve survival one year after the transplant. The trial involved 32 participants and used a special drug regimen to help the body accept the new cells.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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All Children's Hospital
St. Petersburg, Florida, 33701, United States
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Baylor College of Medicine
Houston, Texas, 77030, United States
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Children's Hospital and Research Center Oakland
Oakland, California, 94618, United States
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Children's Hospital of Los Angeles
Los Angeles, California, 90027, United States
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Children's Hospital of Wisconsin/Midwest Children's Cancer
Milwaukee, Wisconsin, 53211, United States
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Children's Mercy Hospital and Clinics
Kansas City, Missouri, 64108, United States
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Children's National Medical Center
Washington D.C., District of Columbia, 20010, United States
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City of Hope National Medical Center
Duarte, California, 91010, United States
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Duke University Medical Center
Durham, North Carolina, 27705, United States
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Fred Hutchinson Cancer Research Center
Seattle, Washington, 98109, United States
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H. Lee Moffitt Cancer Center
Tampa, Florida, 33624, United States
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Hackensack University Medical Center
Hackensack, New Jersey, 07601, United States
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Indiana University Medical Center/ Riley Hospital for Children
Indianapolis, Indiana, 46202, United States
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Johns Hopkins Unversity
Baltimore, Maryland, 21231, United States
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Karmanos Cancer Institute/Children's Hospital of Michigan
Detroit, Michigan, 48201, United States
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Miami Children's Hospital
Miami, Florida, 33155, United States
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Northside Hospital
Atlanta, Georgia, 30342, United States
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Oregon Health and Science University
Portland, Oregon, 97239-3098, United States
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Penn State College of Medicine/The Milton S. Hershey Medical Center
Hershey, Pennsylvania, 17033, United States
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Roswell Park Cancer Institute
Buffalo, New York, 14263, United States
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Stanford Hospital and Clinics
Stanford, California, 94305, United States
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Texas Transplant Institute
San Antonio, Texas, 78229, United States
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University of Florida College of Medicine
Gainesville, Florida, 32610, United States
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University of Louisville/Kosair Children's Hospital
Louisville, Kentucky, 40202, United States
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University of Michigan Medical Center
Ann Arbor, Michigan, 48105, United States
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University of Pennsylvania Cancer Center
Philadelphia, Pennsylvania, 19104, United States
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University of Texas/MD Anderson Cancer Center
Houston, Texas, 77030, United States
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Washington University/Barnes Jewish Hospital
St Louis, Missouri, 63110, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a gentler chemo-radiation combo make stem cell transplants safer for blood cancers?
- Half-Matched stem cell transplant offers hope for children with blood disorders
- New transplant approach aims to tame bone marrow failure
- New hope for older adults with rare blood disorder: safer transplant regimen under study
- New drug combo shows promise for rare bone marrow failure
- New drug combo shows promise for rare blood disorder