New stem cell transplant could help kids with blood cancer avoid severe side effects

NCT ID NCT03431090

First seen Apr 08, 2026 · Last updated May 23, 2026 · Updated 9 times

Summary

This study is testing a new way to do stem cell transplants for children with blood cancers or bone marrow disorders. Instead of needing a perfectly matched donor, doctors use a partially matched family donor and remove certain immune cells from the donated cells to reduce the risk of graft-versus-host disease (GVHD), a serious complication. The goal is to see if this approach helps the new cells grow faster and with fewer side effects. About 20 children will take part in this early-phase trial.

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Contacts and locations

Locations

  • Nationwide Children's Hospital

    Columbus, Ohio, 43205, United States

Conditions

Explore the condition pages connected to this study.