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Collagen gel could offer a Needle-Free fix for gum disease

NCT ID NCT07700628

Completed Disease control Sponsor: Studio Odontoiatrico Dott. G. Tarquini Source: ClinicalTrials.gov ↗

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This study investigates whether a collagen hydrogel called H42 can help treat deep gum pockets caused by periodontitis or peri-implantitis. Researchers will measure changes in pocket depth, plaque, gum attachment, and bleeding over 90 days in adults aged 25 to 65 with 1 to 5 gum defects. The study also tracks pain and healing after treatment. It is a retrospective review of how H42 was used in standard practice, not a controlled experiment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a collagen hydrogel medical device called H42
What this could lead to
If successful, H42 could offer a simple, non-surgical option to reduce gum pocket depth and improve gum health in people with periodontitis or peri-implantitis.
What could go wrong
This is a small, retrospective study without a control group, so results may not prove effectiveness. The device is new and long-term benefits or risks are unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Peri-Implantitis Periodontal Pocket periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERI IMPLANTITIS PERIODONTAL POCKET

Contacts and locations

Locations

  • Studi Odontoiatrici Papa e Di Stefano

    Caserta, CE, 81100, Italy

  • Studio Odontoiatrico Dott. G. Tarquini

    Roma, RM, 00179, Italy

  • Studio odontoiatrico Sao di De Rosa Nicola e Del Giudice Marina

    Naples, 80122, Italy

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