Weight loss shot moves to monthly dosing in new trial

NCT ID NCT07292441

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Phase 3 study tests whether switching to a once-monthly injection of GZR18 can help 500 overweight or obese adults maintain weight loss for an additional 24 weeks. All participants previously completed a year of biweekly GZR18 treatment. The study measures changes in body weight, waist size, and other health markers while everyone follows a regular diet and exercise plan.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

GZR18 injection

What this could lead to

If successful, this could show that a once-monthly injection helps maintain or continue weight loss over 24 weeks, offering a more convenient option for managing obesity.

What could go wrong

This is an extension study, so participants already benefited from the initial 52-week treatment. Results may not apply to new users, and weight regain or side effects are possible with less frequent dosing.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Study site 01

    NOT_YET_RECRUITING

    Beijing, Beijing Municipality, Beijing, China

  • Study site 01

    RECRUITING

    Beijing, Beijing Municipality, Beijing, China

    Contact Phone: •••-•••-••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••