New hope for transplant patients: simpler drug combo may reduce severe side effects

NCT ID NCT06252870

First seen Feb 01, 2026 · Last updated May 12, 2026 · Updated 10 times

Summary

This study tests two different chemotherapy conditioning plans combined with a single drug (cyclophosphamide and methotrexate) to prevent graft-versus-host disease (GVHD) after a stem cell transplant. About 82 adults with blood cancer who have a matched donor will participate. The goal is to see if a simpler drug approach can control GVHD while reducing side effects and improving quality of life.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU Angers

    RECRUITING

    Angers, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU Brest

    RECRUITING

    Brest, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU Nantes

    RECRUITING

    Nantes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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