Fiber from fungus could boost gut health, early study hints

NCT ID NCT03773900

Completed Knowledge-focused Sponsor: Hospices Civils de Lyon Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether taking a daily fiber supplement called chitin-glucan for three weeks could change gut bacteria and improve health markers in 19 adults with abdominal obesity and cardiometabolic risk. Participants took either the fiber or a placebo powder mixed in water. The researchers measured changes in gut bacteria, fatty acids, and digestive tolerance. This is a small, early study to see if the fiber has any effect.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Chitin-glucan fiber (from Aspergillus niger)
What this could lead to: If it works, this could point toward a simple dietary supplement to improve gut health and reduce cardiometabolic risk.
What could go wrong: This is a very small, early study with only 19 people. Results may not apply to everyone, and the fiber might cause digestive discomfort.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Obesity, Abdominal

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ABDOMINAL OBESITY CARDIOMETABOLIC RISK

Contacts and locations

Locations

Centre de Recherche en Nutrition Humaine Rhône-Alpes - Centre hospitalier Lyon Sud

Pierre-Bénite, 69310, France

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