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Scientists probe gut Microbiome's role in lung cancer therapy

NCT ID NCT06221800

Recruiting now Knowledge-focused Sponsor: University of California, Irvine Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study is looking at the gut microbiome—the collection of bacteria in your digestive system—in people with advanced non-small cell lung cancer. Researchers will collect stool and saliva samples before and during standard cancer treatment to see if the diversity of gut bacteria is linked to how well the treatment works or what side effects occur. The goal is simply to gather information, not to test a new drug or therapy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could reveal links between gut microbiome composition and treatment response or side effects in lung cancer patients.
What could go wrong
This is a small, early pilot study (82 participants) that only observes and measures—it does not test a new treatment. Results may not lead to direct clinical changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NON-SMALL CELL LUNG CANCER

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Chao Family Comprehensive Cancer Center University of California, Irvine

    RECRUITING

    Orange, California, 92868, United States

    Contact Email: •••••@•••••

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