Gut check: do probiotics or postbiotics help during antibiotics?
NCT ID NCT07594860
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether taking a probiotic (live bacteria) or a postbiotic (heat-inactivated bacteria) can keep the gut microbiome healthy while people take antibiotics. About 126 healthy adults will receive one of these supplements or a placebo daily for 28 days. Researchers will measure changes in gut bacteria diversity to see if either supplement helps maintain balance.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
probiotic (live bacteria) and postbiotic (heat-inactivated bacteria)
What this could lead to
If it works, this could point toward a simple supplement to protect gut health during antibiotic use.
What could go wrong
This is a small, early pilot study in healthy adults, so results may not apply to sick people or lead to a proven product. The supplements may show no benefit over placebo.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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General Hospital of Thessaloniki Papageorgiou
Thessaloniki, 56429, Greece
Contact Phone: •••-•••-•••• Email: •••••@•••••