Gut health fix for HIV fatty liver? early trial tests probiotics

NCT ID NCT06113003

Ongoing Disease control Sponsor: Vanderbilt University Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase study tests whether taking prebiotic fiber and probiotics can improve fatty liver disease in people with HIV. Researchers believe changes in gut bacteria may contribute to liver problems. The trial involves 63 participants and measures liver fat and gut health markers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Wheat dextrin fiber (prebiotic) and probiotic packet
What this could lead to: If it works, this could point toward a simple dietary supplement approach to help manage fatty liver disease in people with HIV.
What could go wrong: This is a very early, small study (63 participants) testing only short-term markers, not long-term health outcomes. The supplements may not produce meaningful improvement.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease metabolic dysfunction-associated steatotic liver disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV METABOLIC ASSOCIATED STEATOTIC LIVER DISEASE NON-ALCOHOLIC FATTY LIVER DISEASE

Contacts and locations

Locations

Vanderbilt University Medical Center

Nashville, Tennessee, 37232, United States

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