Gel and bone graft combo aims to regrow Gum-Damaged bone
NCT ID NCT07522684
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a gel made from polynucleotide and hyaluronic acid, combined with a bone graft, can help repair bone defects caused by advanced gum disease. 66 adults with severe periodontitis will receive either standard surgery, surgery with bone graft alone, or surgery with both the gel and bone graft. Researchers will measure bone and gum healing over 12 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
polynucleotide and hyaluronic acid gel combined with xenogeneic bone graft
What this could lead to
If successful, this could offer a better way to regenerate bone and tissue around teeth damaged by gum disease, improving tooth stability and reducing the need for extractions.
What could go wrong
This is a small, early-stage trial with only 66 people, so results may not apply to everyone. The gel is new for this use, and its benefits over standard treatments are not yet proven.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Ribeirão Preto School of Dentistry, University of São Paulo
RECRUITINGRibeirão Preto, São Paulo, 14040904, Brazil
Contact Phone: •••-•••-•••• Email: •••••@•••••