Gum disease treatment: can a hyaluronic acid gel regrow bone as well as the standard?

NCT ID NCT07339605

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a hyaluronic acid gel can help regrow bone lost to severe gum disease, compared to the standard enamel matrix derivative gel or no gel at all. All treatments use a minimally invasive, non-surgical technique. Sixty adults with advanced periodontitis will be followed for one year to measure bone fill and patient satisfaction.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

hyaluronic acid gel and enamel matrix derivative

What this could lead to

If successful, this could offer a simpler, less invasive option for regenerating bone lost to gum disease, potentially reducing the need for surgery.

What could go wrong

This is a small, early-stage trial with only 60 participants. The results may not apply to everyone, and the benefits over standard care are still uncertain.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Alveolar Bone Loss disease human disease periodontitis periodontitis, aggressive 1

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Clínica Odontológica de la Universidad de Valencia

    RECRUITING

    Valencia, Valencia, 46010, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••