Could a blood pressure drug ease pain from opioids?

NCT ID NCT01681264

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looked at whether adding guanfacine (a blood pressure medicine) to morphine could reduce pain sensitivity and tolerance in people with chronic neck or back pain. The study planned to enroll 137 adults who had not taken opioids recently. However, the study was terminated early, so results are limited.

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Conditions

The condition(s) this trial relates to.

agnosia Back Pain Chronic Pain chronic pain syndrome Neck Pain Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Center for Translational Pain Research

    Boston, Massachusetts, 02114, United States