Could a blood pressure drug make painkillers work better?

NCT ID NCT01681264

First seen Nov 06, 2025 · Last updated May 15, 2026 · Updated 19 times

Summary

This study looked at whether adding guanfacine (a blood pressure medicine) to morphine could reduce pain sensitivity in people with chronic neck or back pain. Researchers planned to enroll 137 adults who had not taken opioids recently. The study was terminated early, so results are limited.

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Contacts and locations

Locations

  • Center for Translational Pain Research

    Boston, Massachusetts, 02114, United States

Conditions

Explore the condition pages connected to this study.