Gene therapy for dry AMD shows promise but trial halted early
NCT ID NCT03846193
First seen Feb 02, 2026 · Last updated May 15, 2026 · Updated 10 times
Summary
This early-phase study tested a single injection of GT005 gene therapy in 56 people with dry age-related macular degeneration (AMD), a leading cause of vision loss. The goal was to check safety and how well the treatment worked. The trial was stopped early, but results help guide future research.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Bristol Eye Hospital
Bristol, United Kingdom
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Cincinnati Eye Institute
Cincinnati, Ohio, 45242, United States
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Manchester Eye Hospital
Manchester, United Kingdom
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Mid-Atlantic Retina
Philadelphia, Pennsylvania, 19107, United States
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Midwest Eye Institute
Indianapolis, Indiana, 46290, United States
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Moorfields Eye Hospital
London, United Kingdom
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Ophthalamic Consultants of Boston (OCB)
Boston, Massachusetts, 02114, United States
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Oxford University Hospital
Oxford, United Kingdom
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Pepose Vision Institute
Chesterfield, Missouri, 63017, United States
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Retina Clinic London
London, W1G 7LA, United Kingdom
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Sierra Eye Associates
Reno, Nevada, 89502, United States
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Sunderland Eye Infirmary
Sunderland, United Kingdom
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Wolfe Eye Clinic
West Des Moines, Iowa, 50266, United States
Conditions
Explore the condition pages connected to this study.