New pill combo targets Hard-to-Treat cancers in early trial
NCT ID NCT06077877
First seen Feb 02, 2026 · Last updated Apr 30, 2026 · Updated 13 times
Summary
This study tests a new oral drug (GSK4524101) alone and with another drug (niraparib) in adults with advanced solid tumors that have not responded to standard treatments. The goal is to find the safest dose and see if the combination shrinks tumors. About 42 participants will take part in two phases: dose finding and dose expansion.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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GSK Investigational Site
San Francisco, California, 94158, United States
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GSK Investigational Site
St Louis, Missouri, 63110, United States
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GSK Investigational Site
Dallas, Texas, 75230, United States
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GSK Investigational Site
Houston, Texas, 77030, United States
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GSK Investigational Site
San Antonio, Texas, 78229, United States
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GSK Investigational Site
Fairfax, Virginia, 22031, United States
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GSK Investigational Site
Edmonton, Alberta, T6G 1Z2, Canada
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GSK Investigational Site
Toronto, Ontario, M5G 2M9, Canada
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GSK Investigational Site
Montreal, Quebec, H4A 3J1, Canada
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GSK Investigational Site
Panama City, Panama
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GSK Investigational Site
Punta Pacifica Panama City Panama, Panama
Conditions
Explore the condition pages connected to this study.