New drug targets Hard-to-Treat cancers missing PTEN gene
NCT ID NCT04439188
First seen Nov 01, 2025 · Last updated May 31, 2026 · Updated 33 times
Summary
This study tests a drug called GSK2636771 in 35 adults with advanced cancers that have lost the PTEN protein. The drug blocks a protein (PI3K-beta) that helps these cancer cells grow. The goal is to see if the drug can shrink tumors or stop them from growing. This is a phase II trial, meaning it is still in early testing for effectiveness.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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ECOG-ACRIN Cancer Research Group
Philadelphia, Pennsylvania, 19103, United States
Conditions
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