Can group brain training slow Parkinson's cognitive decline?
NCT ID NCT07813156
First seen Sep 10, 2026 · Last updated Sep 11, 2026 · Updated 1 time
Summary
Researchers are testing a new group-based cognitive rehabilitation program for people with early Parkinson's disease who have mild thinking complaints. The program, called LifeCOG-PD, runs for seven 90-minute sessions at a hospital, with 3 to 4 patients per group. Sessions cover practical topics like working memory, attention, and planning, tailored to each person's goals. The study checks whether patients can complete the program and whether it helps maintain daily independence and quality of life.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- a group-based cognitive rehabilitation program called LifeCOG-PD
- What this could lead to
- If it works, structured group sessions could become a standard, drug-free way to help people with early Parkinson's protect their thinking skills and stay independent longer.
- What could go wrong
- This is a small feasibility study of 24 people, so it cannot prove the program works. Participants may drop out, and any benefits seen in a group setting may not last or apply to everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 24 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Sep 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * • Men or women ≥18 years old, diagnosed with idiopathic Parkinson's disease according to the official diagnostic criteria defined by the Movement Disorder Society (MDS) ; * Without cognitive impairment based on neuropsychological evaluation or meeting level 2 Mild Cognitive Impairment (MCI) criteria defined by the MDS, and presenting an early subjective cognitive complaint defined by a score between 1 and 8 on the Subjective Cognitive Complaints Questionnaire for Parkinson's Disease (SCCQ-PD) * Non-demented according to MDS criteria * Ability to understand the protocol; * Ability to provide free and informed consent; * Patients covered by a social insurance system. Exclusion Criteria: * • Any associated neurological disorder or active psychiatric pathology, including severe depressive episode or active psychotic episode. Participants with a Beck Depression Inventory (BDI-II) score above 21 will be excluded from the study and referred to an appropriate healthcare professional for further evaluation and follow-up as needed. * Patients meeting the criteria for Parkinson's disease dementia * Any clinical sign suggesting atypical parkinsonian syndrome (ocular motor disorder, cognitive impairment, apraxia, early falls). * Pregnant or breastfeeding women * Participants under legal protection measures such as judicial protection, deprivation of liberty, curatorship, or guardianship.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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CHU de Clermont-Fd
Clermont-Ferrand, 63000, France
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