Grape powder may keep heart rhythm steady after surgery

NCT ID NCT05991700

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether a concentrated grape powder, taken for three days before heart surgery, can prevent a common complication called post-operative atrial fibrillation (POAF). POAF is an irregular heartbeat thought to be triggered by inflammation after surgery. The trial will include 70 adults aged 50-79 undergoing mitral valve repair. Participants will either receive the grape powder or a placebo, and researchers will monitor heart rhythm and inflammation markers.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Freeze-dried grape powder
What this could lead to
If it works, this could offer a simple, natural way to prevent a common heart surgery complication without risky side effects.
What could go wrong
This is an early Phase 1/2 trial with only 70 people, so results may not apply widely. The effect may be small or not work at all.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Michigan - Michigan Medicine

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

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