Grape powder may keep heart rhythm steady after surgery

NCT ID NCT05991700

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a concentrated grape powder, taken for three days before heart surgery, can prevent a common complication called post-operative atrial fibrillation (POAF). POAF is an irregular heartbeat thought to be triggered by inflammation after surgery. The trial will include 70 adults aged 50-79 undergoing mitral valve repair. Participants will either receive the grape powder or a placebo, and researchers will monitor heart rhythm and inflammation markers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Freeze-dried grape powder

What this could lead to

If it works, this could offer a simple, natural way to prevent a common heart surgery complication without risky side effects.

What could go wrong

This is an early Phase 1/2 trial with only 70 people, so results may not apply widely. The effect may be small or not work at all.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Michigan - Michigan Medicine

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact