Grape extract and exercise: a natural combo for blood pressure?

NCT ID NCT06985407

Completed Disease control Sponsor: University of Castilla-La Mancha Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether taking grape extract, a supplement rich in polyphenols, could improve blood pressure and blood vessel function after exercise in people with slightly high blood pressure (prehypertension). Ten sedentary adults took either grape extract or a placebo for a week, then switched after a break. Researchers measured blood pressure and artery function right after exercise and over 24 hours. The goal was to see if the combination works better than exercise alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: grape extract (VinteraTM Premium OPC)
What this could lead to: If it works, this could point toward a natural supplement to help control blood pressure when paired with exercise.
What could go wrong: This is a very small, early study with only 10 people, so results may not apply to everyone. The effects might be small or not last long.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BLOOD PRESSURE MONITORING, AMBULATORY EXERCISE RESPONSE POLYPHENOL

Contacts and locations

Locations

UCLM

Toledo, Spain

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