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Can a simple heart test predict who benefits most from exercise in old age?

NCT ID NCT07702227

Knowledge-focused Sponsor: Çanakkale Onsekiz Mart University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 14, 2026 · Last updated Aug 05, 2026 · Updated 3 times

Summary

This study looks at how healthy older adults aged 60 to 81 respond to a 12-week exercise program that includes walking, strength, balance, and flexibility exercises. Participants are randomly assigned to either the exercise group or a control group. The researchers measure changes in walking distance, leg strength, and mobility, and also check heart rate variability to see if it can predict who improves the most. The goal is to find simple ways to personalize exercise programs for older adults.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a 12-week supervised multicomponent exercise program including aerobic walking, resistance, balance, agility, and flexibility exercises
What this could lead to
If successful, this study could help identify simple markers that predict which older adults benefit most from exercise, allowing for more personalized fitness programs.
What could go wrong
This is a small, early-stage exploratory study with only 40 participants. The results may not apply to all older adults, and the link between heart rate variability and exercise response may not be clear.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Jun 2026

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 to 81 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * being 60 years of age or older, * being able to walk independently, * not having any serious cardiovascular, neurological, or musculoskeletal disease that would prevent exercise. * do not use medications that may affect autonomic nervous system function * Participants with controlled hypertension who were using stable routine medication were eligible, provided that the screening physician considered them medically suitable for exercise participation. Exclusion Criteria: * diagnosed cardiac arrhythmia, * uncontrolled hypertension, * use of medications that may affect autonomic nervous system function, * inability to perform functional performance tests. * Uncontrolled hypertension. Regular medication use was reviewed during medical screening. Participants were excluded when a medication or its adverse effects were considered to substantially compromise exercise safety, cardiac rhythm, or the ability to complete the exercise and assessment procedures.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Aging Exercise response Functional capacity Heart rate variability (HRV) Older adults (60 - 85 years old)

Contacts and locations

Locations

  • Canakkale Onsekiz Mart University

    Çanakkale, 17100, Turkey (Türkiye)

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