New drug combo aims to keep advanced lung cancer in check

NCT ID NCT07110103

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tests whether adding golidocitinib to standard PD-1 inhibitor maintenance therapy can help people with extensive-stage small cell lung cancer (SCLC) stay progression-free longer. Twenty adults who have not yet been treated for their advanced SCLC will receive the drug combination after initial chemotherapy. The study is open-label and single-arm, meaning everyone gets the experimental treatment, and it is currently recruiting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

golidocitinib (AZD4205) combined with PD-1 inhibitors

What this could lead to

If successful, this could offer a new maintenance treatment option to help control extensive-stage small cell lung cancer and potentially extend the time before the disease worsens.

What could go wrong

This is a small, early-phase (Phase 2) study with only 20 participants, so results may not apply broadly. The combination therapy may cause side effects or fail to improve outcomes compared to standard care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cancer Hospital, Chinese Academy of Medical Sciences

    RECRUITING

    Beijing, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xinqiao Hospital, Third Military Medical University

    RECRUITING

    Chongqing, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••