Tailored support for seniors may speed recovery after CAR-T cancer treatment

NCT ID NCT06052826

Recruiting now Symptom relief Sponsor: City of Hope Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a geriatric assessment—checking physical function, thinking skills, and nutrition—followed by tailored support (physical therapy, delirium prevention, and nutritional help) can help people aged 60 and older recover faster after CAR-T therapy for B-cell non-Hodgkin lymphoma or multiple myeloma. About 164 participants will be split into two groups: one gets the extra support, the other gets standard care. The main goal is to see if the extra support improves physical function 30 days after treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: geriatric assessment and tailored interventions (physical therapy, cognitive education, nutritional support)
What this could lead to: If it works, this could show that personalized geriatric care helps older adults recover faster and with fewer side effects after CAR-T therapy.
What could go wrong: This is a mid-stage trial with 164 participants, so results may not apply to everyone. The interventions are supportive, not a direct treatment for the cancer itself.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

B-cell neoplasm B-cell non-Hodgkin lymphoma plasma cell myeloma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

B-CELL NON-HODGKIN LYMPHOMA MULTIPLE MYELOMA

Contacts and locations

Locations

City of Hope Medical Center
RECRUITING

Duarte, California, 91010, United States

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