Heart drug gel might soothe heel pain in new trial

NCT ID NCT07480876

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether applying a nitroglycerin gel (glyceryl trinitrate) to the heel using ultrasound (phonophoresis) can reduce pain and thickening of the plantar fascia. Eighty adults with chronic plantar fasciitis will receive either the gel plus exercises or exercises alone. The goal is to see if the gel helps more than standard care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

glyceryl trinitrate gel

What this could lead to

If it works, this could offer a new non-surgical option to ease pain and improve function for people with stubborn plantar fasciitis.

What could go wrong

This is a small, early-stage trial with only 80 participants, so results may not apply to everyone. The gel can cause headaches or skin irritation, and the benefit over standard care is unproven.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

plantar fasciitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cairo university

    Cairo, Cairo Governorate, 11311, Egypt

    Contact Phone: •••-•••-•••• Email: •••••@•••••