Can a mushroom-derived supplement plus exercise fight muscle loss in aging?

NCT ID NCT06629805

Completed Disease control Sponsor: Pusan National University Yangsan Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jul 29, 2026 · Updated 3 times

Summary

This completed study tested whether a daily β-glucan supplement (1,000 mg) combined with regular exercise could improve muscle strength, mass, and function in 116 adults with relative sarcopenia. Participants took either the supplement or a placebo for 12 weeks while following an exercise program. The goal was to see if this combination could help counteract age-related muscle decline.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Aureobasidium pullulans produced β-glucan (a dietary supplement)
What this could lead to: If effective, this supplement plus exercise could offer a simple, non-drug way to help older adults maintain muscle strength and function.
What could go wrong: This is a small, completed trial with 116 participants. The supplement is not a proven treatment, and results may not apply to everyone with sarcopenia.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SARCOPENIA

Contacts and locations

Locations

Pusan National University Yangsan Hospital

Yangsan, 50612, South Korea

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Other studies related to the condition(s) this trial covers.