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Eye surgery showdown: which drainage device placement saves more vision cells?

NCT ID NCT05924477

Recruiting now Disease control Sponsor: University of Pennsylvania Source: ClinicalTrials.gov ↗

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This clinical trial compares two ways to place a glaucoma drainage device during surgery: one in the front chamber of the eye and one in a small space behind it. The goal is to see which method causes less loss of important cells on the inner surface of the cornea. The study involves 226 adults with glaucoma that is not well controlled by medication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
glaucoma drainage device implantation surgery with tube placement in either the ciliary sulcus or the anterior chamber
What this could lead to
If successful, this could identify a surgical technique that better preserves the eye's inner lining cells, potentially improving long-term vision outcomes for glaucoma patients.
What could go wrong
This is a surgical technique comparison, not a new drug or cure. Results may show no significant difference between placements, and individual outcomes can vary based on patient anatomy and surgeon skill.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

glaucoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GLAUCOMA

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Bascom Palmer Eye Institute

    RECRUITING

    Miami, Florida, 33136, United States

    Contact

  • Diablo Eye Associates

    RECRUITING

    Walnut Creek, California, 94598, United States

    Contact

  • Massachusetts Eye and Ear

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact

  • Prism Eye Institute, University of Toronto

    RECRUITING

    Toronto, Canada

    Contact

  • University of Buffalo/State University of New York

    RECRUITING

    Buffalo, New York, 14203, United States

    Contact

  • University of California San Francisco

    RECRUITING

    San Francisco, California, 94143, United States

    Contact

  • University of North Carolina at Chapel Hill

    RECRUITING

    Chapel Hill, North Carolina, 27517, United States

    Contact

  • Wilmer Eye Institute, Johns Hopkins University

    RECRUITING

    Baltimore, Maryland, 21287, United States

    Contact

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