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Could a squeeze of acid make gum Dark-Spot removal look better?

NCT ID NCT07708792

Symptom relief Sponsor: Dijlah University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study tests whether applying citric acid during a procedure to remove dark gum pigmentation leads to better-looking results and faster healing. Adults aged 18 to 50 with natural dark gums will receive either standard depigmentation or depigmentation plus acid. The researchers will compare esthetic improvement, pain, and how long the results last.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
citric acid applied topically during gingival depigmentation
What this could lead to
If it works, this could offer a simple way to improve the appearance and healing of gum depigmentation procedures.
What could go wrong
This is a small pilot study with only 30 participants, so results may not apply to everyone. Adding acid could also cause irritation or uneven healing.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 50 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18-50 years. * Presence of physiologic gingival melanin pigmentation requiring treatment. * Good general health. * Good periodontal health or a healthy periodontium after initial periodontal therapy. * Willingness to participate and provide written informed consent. * Ability to attend all follow-up visits. Exclusion Criteria: * Current smokers or tobacco users. * Pregnancy or breastfeeding. * History of systemic diseases that may affect wound healing (e.g., uncontrolled diabetes or immunocompromised conditions). * Use of medications known to affect gingival pigmentation or wound healing. * Previous gingival depigmentation treatment in the study area. * Active periodontal disease or oral infection. Known allergy or hypersensitivity to the study acid or related materials.

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Conditions

The condition(s) this trial relates to.

vitiligo

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Gingival pigmentation

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

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