New hepatitis b drug enters first human tests

NCT ID NCT07024641

First seen Oct 31, 2025 · Last updated Jun 21, 2026 · Updated 33 times

Summary

This early-stage trial is testing a new drug called GIGA-2339 in 48 people with chronic hepatitis B. The main goal is to check if the drug is safe and how the body processes it. Participants receive either the drug or a placebo by IV infusion, and researchers will monitor for side effects and measure drug levels in the blood.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Grifols Investigate Site

    RECRUITING

    Concord, New South Wales, 2139, Australia

    Contact

  • Grifols Investigative Site

    RECRUITING

    Peachtree Corners, Georgia, 30071, United States

    Contact

  • Grifols Investigative Site

    RECRUITING

    Iowa City, Iowa, 52242, United States

    Contact

  • Grifols Investigative Site

    RECRUITING

    Lenexa, Kansas, 66219, United States

    Contact

  • Grifols Investigative site

    RECRUITING

    Chandler, Arizona, 85225, United States

    Contact

  • Grifols Investigative site

    RECRUITING

    Huntington Beach, California, 92647, United States

    Contact

  • Grifols Investigative site

    RECRUITING

    Lake Forest, California, 92630, United States

    Contact

  • Grifols Investigative site

    RECRUITING

    Long Beach, California, 90805, United States

    Contact

  • Grifols Investigative site

    RECRUITING

    Oakland, California, 94605, United States

    Contact

  • Grifols Investigative site

    RECRUITING

    Baltimore, Maryland, 21287, United States

    Contact

  • Grifols Investigative site

    RECRUITING

    San Antonio, Texas, 78215, United States

    Contact

  • Grifols Investigative site

    RECRUITING

    Webster, Texas, 77598, United States

    Contact

  • Grifols Investigative site

    RECRUITING

    Richmond, Virginia, 23284, United States

    Contact

  • Grifols Investigative site

    RECRUITING

    Fortitude Valley, Queensland, 4006, Australia

    Contact

  • Grifols Investigative site

    RECRUITING

    Hong Kong, Hong Kong Island, Hong Kong

    Contact

  • Grifols Investigative site

    RECRUITING

    Shatin, New Territories, Hong Kong

    Contact

  • Grifols Investigative site

    RECRUITING

    Seogu, Busan, South Korea

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

GIGA-2339 (a drug given by intravenous infusion)

What this could lead to

If successful, this could point toward a new treatment option to help control chronic hepatitis B virus infection.

What could go wrong

This is a very early Phase 1 trial with only 48 participants, focused on safety and dosing. It is not designed to prove effectiveness, and many early-stage drugs do not advance.

Conditions

The condition(s) this trial relates to.

chronic hepatitis B virus infection hepatitis B virus infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.