New blood test may sharpen diagnosis of autoimmune liver disease
NCT ID NCT05810480
First seen Jul 15, 2026 · Last updated Jul 16, 2026 · Updated 1 time
Summary
This study evaluates whether a blood test measuring polyreactive immunoglobulin G (pIgG) can more accurately diagnose autoimmune hepatitis (AIH) and distinguish it from other liver conditions. Researchers will collect blood samples from 400 adults undergoing liver biopsy for suspected liver disease. The goal is to see if pIgG testing improves upon standard autoantibody tests, especially in cases where conventional tests are negative or misleading.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- polyreactive immunoglobulin G (pIgG) diagnostic test
- What this could lead to
- If successful, this test could provide a more accurate way to diagnose autoimmune hepatitis, reducing misdiagnosis and unnecessary treatments.
- What could go wrong
- This is a diagnostic study, not a treatment trial. The test may not prove superior to existing methods, and results may not apply to all patient groups.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Hannover Medical School
RECRUITINGHanover, 30625, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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RWTH Aachen
NOT_YET_RECRUITINGAachen, Germany
Contact Email: •••••@•••••
Contact Email: •••••@•••••
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Rostock University Medical Centre
NOT_YET_RECRUITINGRostock, 18057, Germany
Contact
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University Hospital Schleswig-Holstein, Location Lübeck
NOT_YET_RECRUITINGLübeck, 23562, Germany
Contact
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University Medical Center Hamburg-Eppendorf
NOT_YET_RECRUITINGHamburg, 20251, Germany
Contact
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University Medical Center Heidelberg
NOT_YET_RECRUITINGHeidelberg, 69120, Germany
Contact
Contact
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