New drug cocktail shows promise for liver cancer in hepatitis b patients

NCT ID NCT04180072

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a combination of two drugs, atezolizumab and bevacizumab, in 51 people with advanced liver cancer who also have chronic hepatitis B. The goal is to see if the treatment can shrink tumors and control the disease. Participants receive the drugs every three weeks, and researchers monitor tumor response and side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

atezolizumab (Tecentriq) and bevacizumab (Avastin)

What this could lead to

If successful, this could offer a new treatment option for advanced liver cancer in people with chronic hepatitis B, potentially shrinking tumors and extending life.

What could go wrong

This is a small, single-arm trial with no comparison group, so results may not be definitive. The drugs can cause serious side effects like liver damage or bleeding.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic hepatitis B virus infection hepatocellular carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Chang Gung Memorial Hospital

    Linkou District, Taiwan

  • China Medical University Hospital

    Taichung, Taiwan

  • Mackay Memorial Hospital

    Taipei, Taiwan

  • National Cheng Kung University Hospital

    Tainan, Taiwan

  • National Taiwan University Hospital

    Taipei, Taiwan

  • Taichung Veterans General Hospital

    Taichung, Taiwan

  • Taipei Veterans General Hospital

    Taipei, Taiwan