Gene-Guided reflux drug may tame childhood asthma
NCT ID NCT03015610
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested whether adjusting the dose of a common acid reflux medicine (lansoprazole) based on a child's genes could improve asthma control. 41 children aged 6-17 with uncontrolled asthma and mild reflux participated. Researchers measured changes in asthma symptoms and reflux over 24 weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
lansoprazole
What this could lead to
If successful, this could lead to personalized dosing of acid reflux medicine to better control asthma in children.
What could go wrong
This is a small, completed Phase 3 trial with only 41 participants, so results may not apply to all children. The benefit of gene-guided dosing over standard care remains uncertain.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Duke University Medical Center
Durham, North Carolina, 27710, United States
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Nemours Children's Specialty Care
Jacksonville, Florida, 32207, United States