New nerve block could ease pain after knee surgery
NCT ID NCT06639503
First seen Feb 05, 2026 · Last updated Jun 23, 2026 · Updated 25 times
Summary
This study tests whether injecting numbing medication around specific knee nerves (a nerve block) provides better pain relief after surgery for a broken shinbone (tibial plateau fracture) than the standard approach of numbing just the surgical cut. Researchers will compare pain scores and painkiller use in 38 adults undergoing this surgery. The goal is to find a more effective way to manage post-operative pain.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Chicago
RECRUITINGChicago, Illinois, 60637, United States
Contact Email: •••••@•••••
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
bupivacaine (numbing medication)
What this could lead to
If it works, this could point toward a better way to manage pain after knee fracture surgery, potentially reducing the need for strong painkillers.
What could go wrong
This is a very early, small Phase 1 trial with only 38 participants. The nerve block may not prove more effective than standard care, and there are always risks with any injection, such as infection or nerve damage.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.