Gene test may predict dangerous side effects in breast cancer treatment
NCT ID NCT07582887
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study explores whether certain gene variants (UGT1A1) increase the risk of severe side effects from powerful breast cancer drugs called antibody-drug conjugates. Researchers will enroll 70 adults with advanced breast cancer who are starting treatment with sacituzumab-govitecan, trastuzumab-deruxtecan, or datopotamab-deruxtecan. By analyzing participants' genes and tracking their side effects, the study aims to develop a way to predict who is most at risk, potentially leading to safer, more personalized treatment.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
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The condition terms exactly as the trial's registrant entered them.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Hospital Universitario Clínico San Cecilio
RECRUITINGGranada, Granada, 18016, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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