Chatbot aims to close genetic testing gap for cancer patients

NCT ID NCT06422455

Recruiting now Knowledge-focused Sponsor: University of Southern California Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a computer-generated character (PERLA) can effectively educate cancer patients about genetic testing, compared to a human genetics counselor. Researchers will enroll 800 people with certain cancers, including breast, ovarian, pancreatic, and prostate cancer, especially those from underserved communities. The goal is to see if the computer tool increases the number of patients who actually get genetic testing.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Educational intervention (PERLA conversational agent)
What this could lead to: If successful, this could show that a computer-based tool can help more people from underserved groups get genetic testing for cancer.
What could go wrong: This is an early-stage study comparing two education methods, not testing a new treatment. The computer tool may not work as well as human counselors for some patients.

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Conditions

The condition(s) this trial relates to.

bilateral breast carcinoma breast cancer breast carcinoma breast neoplasm cancer male breast carcinoma malignant exocrine pancreas neoplasm metastatic prostate carcinoma ovarian cancer ovarian carcinoma pancreatic exocrine neoplasm prostate cancer triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CARCINOMA MALE BREAST CARCINOMA MALIGNANT SOLID NEOPLASM METASTATIC PROSTATE CARCINOMA OVARIAN CARCINOMA PANCREATIC EXOCRINE NEOPLASM STAGE IVB PROSTATE CANCER AMERICAN JOINT COMMITTEE ON CANCER V8 TRIPLE-NEGATIVE BREAST CARCINOMA

Contacts and locations

Locations

USC / Norris Comprehensive Cancer Center
RECRUITING

Los Angeles, California, 90033, United States
University of Rochester
RECRUITING

Rochester, New York, 14642, United States

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