Scientists hunt for hidden leukemia genes in families

NCT ID NCT03058588

Recruiting now Knowledge-focused Sponsor: Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks for inherited gene mutations that may raise the risk of acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). Researchers will use advanced genetic testing to compare DNA from affected and unaffected family members. The goal is to find new or known mutations linked to these blood cancers, which could improve understanding of how they run in families.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help identify genetic markers that predict leukemia risk in families, potentially guiding earlier monitoring or prevention strategies.
What could go wrong: This is a small, early-stage observational study with only 20 participants. It aims to discover mutations, not test a treatment, so direct benefits for patients are uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute myeloid leukemia leukemia myelodysplastic syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LEUKEMIA

Contacts and locations

Locations

Chair of Hematology and Bone marrow Transplant Unit
RECRUITING

Brescia, 25123, Italy

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