Azienda Socio Sanitaria Territoriale Degli Spedali Civili Di Brescia

This study looks at how well CAR-T cell therapy works for people with certain blood cancers like lymphoma and leukemia. Researchers will track how the modified immune cells grow and last in the body after infusion. The goal is to see if this treatment is effective in real-world s…

This phase 2 trial is testing whether the immunotherapy drug cemiplimab can delay or prevent cancer progression in people with advanced adrenocortical cancer whose disease has been stabilized by initial chemotherapy. About 31 participants will receive cemiplimab every three weeks…

This study tests whether Eye Movement Desensitization and Reprocessing (EMDR), a therapy proven for PTSD, can help people with borderline personality disorder (BPD). Researchers will give 56 adults 14 weekly EMDR sessions and measure changes in emotional and behavioral symptoms. …

This study looks for inherited gene mutations that may raise the risk of acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). Researchers will use advanced genetic testing to compare DNA from affected and unaffected family members. The goal is to find new or known mu…

This study is not a treatment itself but a research method. It will collect data from nearly 2,000 older adults (60-75) with acute myeloid leukemia (AML) to compare a new drug combination (venetoclax plus decitabine) against standard intensive chemotherapy. Using AI and statistic…

This study involves 135 adults getting a cornea transplant. Surgeons will use a new method to check the health of donor eye tissue before surgery. The goal is to see if this check helps predict how well the transplant will work long-term, reducing the chance of graft failure.