Azienda Socio Sanitaria Territoriale Degli Spedali Civili Di Brescia

This study tests whether the immunotherapy drug cemiplimab can help prevent or delay cancer growth in people with advanced adrenocortical cancer whose disease was controlled by initial chemotherapy. About 31 adults whose tumors did not worsen after 4-6 cycles of chemo will receiv…

This study is for people with certain blood cancers (DLBCL, PMBCL, or ALL) that have not responded to at least two prior treatments. It will track how well the patient's own modified immune cells (CAR-T cells) grow and last in the body after infusion. The goal is to understand ho…

This study looks at whether a therapy called EMDR, which is already used for PTSD, can help people with borderline personality disorder (BPD) manage their emotions and behavior better. Researchers will work with 56 adults who have BPD, with or without PTSD, to see if a short cour…

This study involves 135 adults getting a corneal transplant. Doctors will use a special dye to check the health of donor corneas before surgery. They want to see if this check can predict long-term success and reduce the chance of transplant failure.

This study aims to find gene changes that increase the risk of developing acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) in families. Researchers will use advanced DNA sequencing to test both affected and healthy family members. The goal is to discover new or kn…

This study uses artificial intelligence and real-world patient data to compare a new drug combination (venetoclax plus decitabine) against standard chemotherapy for elderly patients (ages 60-75) with acute myeloid leukemia (AML). Researchers will analyze records from nearly 2,000…