Scientists hunt for genes behind liver disease in cystic fibrosis

NCT ID NCT00804583

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looks at genes, other than the CF gene, that might explain why some people with cystic fibrosis develop severe liver disease while others do not. Researchers are analyzing blood samples and medical records from 154 participants with CF who have serious liver problems. The goal is to find genetic clues that could lead to better understanding and, eventually, new treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this research could point toward new treatments for cystic fibrosis-related liver disease by identifying key genetic factors.

What could go wrong

This is an observational study, not a treatment trial, so it won't directly help participants. It may not find clear genetic links, and any future treatments are years away.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cystic fibrosis cystic fibrosis-related liver disease liver disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The University of North Carolina at Chapel Hill

    Chapel Hill, North Carolina, 27599, United States