Scientists hunt for genes behind liver disease in cystic fibrosis

NCT ID NCT00804583

Ongoing Knowledge-focused Sponsor: University of North Carolina, Chapel Hill Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looks at genes, other than the CF gene, that might explain why some people with cystic fibrosis develop severe liver disease while others do not. Researchers are analyzing blood samples and medical records from 154 participants with CF who have serious liver problems. The goal is to find genetic clues that could lead to better understanding and, eventually, new treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could point toward new treatments for cystic fibrosis-related liver disease by identifying key genetic factors.
What could go wrong: This is an observational study, not a treatment trial, so it won't directly help participants. It may not find clear genetic links, and any future treatments are years away.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cystic fibrosis cystic fibrosis-related liver disease liver disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CYSTIC FIBROSIS LIVER DISEASE

Contacts and locations

Locations

The University of North Carolina at Chapel Hill

Chapel Hill, North Carolina, 27599, United States

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