Scientists build mini livers to unlock genetic secrets of rare bile duct disease

NCT ID NCT06865924

First seen Mar 25, 2026 · Last updated Apr 30, 2026 · Updated 8 times

Summary

This study aims to understand why some people develop a rare, serious liver disease called primary sclerosing cholangitis (PSC). Researchers will create 3D cell models from patient samples to study how specific genetic changes affect bile duct cells. The goal is to identify genetic risk factors and test new treatments in the lab. The study involves 80 adults with or without PSC.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

    RECRUITING

    Milan, MI, 20122, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.