Brain surgery and gene therapy aim to tame Parkinson's symptoms
NCT ID NCT07533591
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase trial tests a new gene therapy for Parkinson's disease. Six participants will receive a virus-based treatment injected into a specific brain area during surgery. Afterward, they take a drug to control abnormal brain activity and improve movement. The main goal is to check safety, not yet to prove it works.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
STP-001 (gene therapy with AAV vector and clozapine)
What this could lead to
If it works, this could point toward a new way to control Parkinson's motor symptoms without long-term medication side effects.
What could go wrong
This is a very early, small trial (6 people) focused on safety, not proof of effectiveness. The approach is experimental and may not work or could cause side effects like brain inflammation or movement problems.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Second Affiliated Hospital, School of Medicine,Zhejiang University
Zhejiang, Province, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••