Gene therapy trial offers hope for hemophilia b patients

NCT ID NCT00979238

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 27 times

Summary

This early-stage study tested a new gene therapy for adults with severe hemophilia B, a bleeding disorder caused by a faulty gene. The treatment uses a harmless virus to deliver a working copy of the factor IX gene into the body. The main goal was to check safety in 14 participants, not yet to prove it works as a cure.

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Contacts and locations

Locations

  • Katharine Dormandy Haemophilia Centre and Haemostasis Unit, University College of London

    London, United Kingdom

  • Scott and White Memorial Hospital

    Temple, Texas, 76508, United States

  • St. Jude Children's Research Hospital

    Memphis, Tennessee, 38119, United States

  • Stanford Medical School

    Stanford, California, 94305, United States

Conditions

Explore the condition pages connected to this study.