New Tile-Shaped radiation device tested for brain tumors
NCT ID NCT04427384
First seen Jun 27, 2026 · Last updated Jul 23, 2026 · Updated 2 times
Summary
This study is tracking 600 people with brain tumors who receive GammaTile therapy during surgery. GammaTile is a device that delivers radiation directly to the tumor site to help prevent regrowth. Researchers are measuring how long tumors stay under control and how patients feel over time.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- GammaTile (a device that delivers radiation directly to the tumor site during surgery)
- What this could lead to
- If successful, this could show that GammaTile is a safe and effective way to control brain tumor regrowth after surgery.
- What could go wrong
- This is an observational study, not a controlled trial, so results may not prove cause and effect. It is still recruiting and outcomes are not yet known.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Abbott Northwestern Hospital
RECRUITINGMinneapolis, Minnesota, 55407, United States
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Advent Health Orlando
RECRUITINGOrlando, Florida, 32803, United States
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Albany Medical Center
RECRUITINGAlbany, New York, 12208, United States
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Allegheny Health Network
RECRUITINGPittsburgh, Pennsylvania, 15212, United States
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Ascension St. Vincent's
RECRUITINGJacksonville, Florida, 32204, United States
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Atlantic Brain & Spine
RECRUITINGWilmington, North Carolina, 28401, United States
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BayCare Health
RECRUITINGClearwater, Florida, 33756, United States
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Baylor St. Luke's Medical Center | Baylor College of Medicine
RECRUITINGHouston, Texas, 77030, United States
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Beth Israel Deaconess Medical Center
RECRUITINGBoston, Massachusetts, 02215, United States
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Beth Israel Deaconess Medical Center
RECRUITINGBoston, Massachusetts, 02215, United States
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Brown University Health
RECRUITINGProvidence, Rhode Island, 02906, United States
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CHI Memorial Hospital, CommonSpirit
RECRUITINGChattanooga, Tennessee, 37404, United States
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California Pacific Medical Center, Sutter health
RECRUITINGSan Francisco, California, 94109, United States
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Centura
NOT_YET_RECRUITINGDenver, Colorado, 80201, United States
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Cleveland Clinic Florida- Weston
RECRUITINGWeston, Florida, 33331, United States
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Clinical Research dep. Davison Place. Englewood Health
NOT_YET_RECRUITINGEnglewood, New Jersey, 07631, United States
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Colorado Brain & Spine Institute: Swedish Campus
RECRUITINGEnglewood, Colorado, 80113, United States
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Desert Regional Medical Center
RECRUITINGPalm Springs, California, 92262, United States
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Eden Medical Center
RECRUITINGCastro Valley, California, 94546, United States
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Florida Health Sciences Center, Inc. d/b/a Tampa General Hospital
RECRUITINGTampa, Florida, 33606, United States
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Goodman Campbell Brain and Spine
RECRUITINGCarmel, Indiana, 46032, United States
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Henry Ford Health System
RECRUITINGDetroit, Michigan, 48202, United States
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HonorHeath Scottsdale Osborn Medical Center
RECRUITINGPhoenix, Arizona, 85027, United States
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Houston Methodist Hospital
RECRUITINGHouston, Texas, 77030, United States
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INOVA Health
RECRUITINGFairfax, Virginia, 22031, United States
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Indiana University, IU Health Methodist Hospital
RECRUITINGIndianapolis, Indiana, 46202, United States
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KUMC Dept of Neurosurgery
RECRUITINGKansas City, Kansas, 66160, United States
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Kettering Health
RECRUITINGKettering, Ohio, 45429, United States
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Mayfield Brain and Spine
RECRUITINGCincinnati, Ohio, 45209, United States
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MemorialCare Health System
RECRUITINGLaguna Hills, California, 92653, United States
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Miami Cancer Institute, Baptist Health South Florida
RECRUITINGMiami, Florida, 33176, United States
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Montefiore Einstein
RECRUITINGThe Bronx, New York, 10467, United States
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Mount Sinai Hospital
ACTIVE_NOT_RECRUITINGNew York, New York, 10029, United States
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Norton Cancer Institute
RECRUITINGLouisville, Kentucky, 40241, United States
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Orlando Health
RECRUITINGOrlando, Florida, 32806, United States
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Penn State Health
RECRUITINGHershey, Pennsylvania, 17033, United States
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Piedmont Healthcare
RECRUITINGAtlanta, Georgia, 30309, United States
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SUNY Upstate Medical Center
RECRUITINGSyracuse, New York, 13210, United States
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St Luke's University Health, Sacred Heart Campus
RECRUITINGAllentown, Pennsylvania, 18102, United States
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St. Alphonsus Regional Medical Center
RECRUITINGBoise, Idaho, 83704, United States
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Texas Oncology-The Woodlands
RECRUITINGThe Woodlands, Texas, 77380, United States
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UCSD Moores Cancer Center
RECRUITINGLa Jolla, California, 92093, United States
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UT Southwestern Simmons Cancer Center
RECRUITINGDallas, Texas, 75235, United States
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Univeristy of Louisville Health
RECRUITINGLouisville, Kentucky, 40202, United States
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University of Arkansas Medical Center
RECRUITINGLittle Rock, Arkansas, 72205, United States
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University of Minnesota
RECRUITINGMinneapolis, Minnesota, 55414, United States
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University of Nebraska
RECRUITINGOmaha, Nebraska, 68198, United States
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University of North Carolina Health
ACTIVE_NOT_RECRUITINGChapel Hill, North Carolina, 27599, United States
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University of Texas Health Science Center of San Antonio
RECRUITINGSan Antonio, Texas, 78229, United States
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Vidant Heath - ECU Medical Center
RECRUITINGGreenville, North Carolina, 27834, United States
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Virginia Mason
RECRUITINGSeattle, Washington, 98101, United States
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Westchester Medical Center
RECRUITINGValhalla, New York, 10595, United States
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Willis-Knighton Medical Center
WITHDRAWNShreveport, Louisiana, 71103, United States
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Winship Cancer Institute of Emory University
RECRUITINGAtlanta, Georgia, 30322, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can trained immune cells outsmart brain tumors?
- Mapping the Brain's hidden damage after radiation in kids
- Digital tests may offer a new way to track brain health in tumor patients
- Mapping the hidden toll of brain radiation on young minds
- Scientists create detailed brain maps to protect language during surgery
- Could a cancer drug shrink recurrent brain tumors?