New drug cocktail shows promise for tough cancers

NCT ID NCT05945823

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 25 times

Summary

This study tests a new combination of drugs (futibatinib plus standard immunotherapy) in adults with advanced esophageal or pancreatic cancer that cannot be removed by surgery. The goal is to see if the combination shrinks tumors and is safe. About 53 people will take part, and they must not have had prior treatment for their advanced cancer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Alliance Cancer Specialists

    Horsham, Pennsylvania, 19044, United States

  • Blue Ridge Cancer Care

    Roanoke, Virginia, 24014, United States

  • Centre Hospitalier Regional Universitaire Poitiers

    Poitiers, 86000, France

  • Centre Hospitalier Regional Universitaire de Lille

    Lille, 59037, France

  • Dallas VA Medical Center

    Dallas, Texas, 75216, United States

  • Gabrail Cancer Center Research LLC

    Canton, Ohio, 44718, United States

  • Gundersen Lutheran Health System

    La Crosse, Wisconsin, 54601, United States

  • Henry Ford Health System

    Detroit, Michigan, 48202, United States

  • Hospital Universitari Vall d'Hebron

    Barcelona, 08035, Spain

  • Hospital Universitario 12 de Octubre

    Madrid, 28041, Spain

  • Inova Schar Cancer Institute

    Fairfax, Virginia, 22031, United States

  • Krankenhaus Nordwest gGmbH

    Frankfurt, 60488, Germany

  • Moffitt Cancer Center and Research Institute

    Tampa, Florida, 33612, United States

  • Mount Sinai Comprehensive Cancer Center

    Miami Beach, Florida, 33140, United States

  • NYU Langone

    New York, New York, 10016, United States

  • Rocky Mountain Cancer Centers Midtown

    Denver, Colorado, 80218, United States

  • Roswell Park Comprehensive Cancer Center (RPCCC) (Roswell Park Cancer Institute (RPCI))

    Buffalo, New York, 14203, United States

  • The Minniti Center - Medical Oncology and Hematology

    Mickleton, New Jersey, 08056, United States

  • Universitaetsmedizin Mainz

    Mainz, 55131, Germany

  • University of California Los Angeles UCLA - Cancer Care - Santa Monica

    Santa Monica, California, 90404, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

  • Virginia Mason Medical Center

    Seattle, Washington, 98101, United States

Conditions

Explore the condition pages connected to this study.