Taiho Oncology, Inc.

This study tests two different doses (20 mg and 16 mg) of the drug futibatinib in people with advanced bile duct cancer that has a specific genetic change (FGFR2 fusion or rearrangement). About 120 participants who have already received chemotherapy will take the drug daily to se…

This study tests an experimental drug called zipalertinib in people with advanced non-small cell lung cancer that has certain changes in the EGFR gene. About 220 adults will take the drug to see if it shrinks tumors and how safe it is. The goal is to control the disease, not cure…

This study looks at how the body handles the cancer drug ASTX727 in people with severe kidney problems compared to those with normal kidneys. About 18 adults with certain blood cancers or solid tumors will take the drug for up to 8 weeks. The goal is to see if the drug is safe an…

This study looks at how the cancer drug ASTX727 works in people with moderate or severe liver problems. It includes 27 adults with certain blood cancers or solid tumors. The goal is to understand how the liver affects the drug's safety and processing in the body.

This study tests an oral drug (ASTX030) that combines two chemotherapy agents to treat certain blood cancers like myelodysplastic syndromes and acute myeloid leukemia. It aims to see if taking a pill is as effective as getting injections. About 316 adults will participate over ro…