Experimental cell therapy takes on tough blood cancers

NCT ID NCT04629729

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-phase study tests a new treatment called FT819 for people with B-cell cancers (lymphoma, CLL, or B-ALL) that have not responded to standard therapies. The goal is to find a safe dose and see if the therapy can shrink tumors. About 54 participants will receive FT819 alone or with another drug (IL-2) to boost its effects.

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Conditions

The condition(s) this trial relates to.

B-cell chronic lymphocytic leukemia B-cell neoplasm leukemia lymphoma precursor B-cell acute lymphoblastic leukemia Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hackensack University Medical Center

    Hackensack, New Jersey, 07601, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Mayo Arizona

    Phoenix, Arizona, 85054, United States

  • Mayo Florida

    Jacksonville, Florida, 32224, United States

  • Mayo Minnesota

    Rochester, Minnesota, 55905, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10021, United States

  • Norton Cancer Institute, St. Matthews Campus

    Louisville, Kentucky, 40207, United States

  • Oregon Health & Sciences University

    Portland, Oregon, 97239, United States

  • Scripps Green Hospital

    La Jolla, California, 92037, United States

  • Stanford Cancer Institute

    Palo Alto, California, 94304, United States

  • The University of Kansas Cancer Center

    Westwood, Kansas, 66205, United States

  • UC Davis

    Davis, California, 95817, United States

  • UCLA Ronald Reagan Medical Center

    Los Angeles, California, 90095, United States

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35294, United States

  • University of Florida

    Gainesville, Florida, 32608, United States

  • University of Iowa

    Iowa City, Iowa, 52242, United States

  • University of Nebraska Medical Center

    Omaha, Nebraska, 68198, United States

  • University of Wisconsin-Madison

    Madison, Wisconsin, 53705, United States