MS patients may soon swap IV drips for quick shots
NCT ID NCT07325292
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This Phase 3 trial tests whether a simple injection of frexalimab every 4 weeks works as well as the standard IV infusion for adults with relapsing or non-active progressive multiple sclerosis. About 160 participants will be randomly assigned to one of the two methods. The study lasts 48 weeks and aims to see if the injection provides similar drug levels and safety.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
frexalimab
What this could lead to
If successful, this could show that a simple injection works as well as an IV infusion for controlling multiple sclerosis, making treatment more convenient.
What could go wrong
This is an early-stage Phase 3 trial with only 160 participants, so results may not apply to everyone. The study compares two ways of giving the same drug, not against a placebo, so it won't prove the drug itself works.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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ANESC Research- Site Number : 8400187
RECRUITINGEl Paso, Texas, 79912, United States
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Advanced Neurology of Colorado- Site Number : 8400148
RECRUITINGFort Collins, Colorado, 80528, United States
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Alabama Neurology Associates- Site Number : 8400115
RECRUITINGHomewood, Alabama, 35209, United States
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Aqualane Clinical Research- Site Number : 8400026
RECRUITINGNaples, Florida, 34105, United States
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Center for Neurology and Spine - Phoenix - East Bell Road- Site Number : 8400195
RECRUITINGPhoenix, Arizona, 85032, United States
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Consultants in Neurology- Site Number : 8400020
RECRUITINGNorthbrook, Illinois, 60062, United States
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Holy Name Medical Center- Site Number : 8400101
RECRUITINGTeaneck, New Jersey, 07666, United States
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Hope Neurology- Site Number : 8400019
RECRUITINGKnoxville, Tennessee, 37922, United States
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Investigational Site Number : 0560001
RECRUITINGBruges, 8000, Belgium
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Investigational Site Number : 0560005
RECRUITINGOverpelt, 3900, Belgium
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Investigational Site Number : 0560006
RECRUITINGGhent, 9000, Belgium
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Investigational Site Number : 0560007
RECRUITINGKortrijk, 8500, Belgium
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Investigational Site Number : 0560008
RECRUITINGBrussels, 1200, Belgium
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Investigational Site Number : 1560004
RECRUITINGChengdu, 610041, China
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Investigational Site Number : 1560005
RECRUITINGBeijing, 100034, China
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Investigational Site Number : 1560010
RECRUITINGJiazhuang, 050000, China
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Investigational Site Number : 1561029
RECRUITINGChengdu, 610072, China
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Investigational Site Number : 3920001
RECRUITINGKyoto, 616-8255, Japan
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Investigational Site Number : 3920008
RECRUITINGYahaba, Iwate, 028-3695, Japan
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Investigational Site Number : 3920017
RECRUITINGSapporo, Hokkaido, 063-0005, Japan
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Joi Life Wellness Group LLC- Site Number : 8400192
RECRUITINGSmyrna, Georgia, 30080, United States
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Michigan Institute for Neurological Disorders- Site Number : 8400004
RECRUITINGFarmington Hills, Michigan, 48334, United States
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Neurology Associates of Ormond Beach- Site Number : 8400086
RECRUITINGOrmond Beach, Florida, 32174, United States
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Neurology of Central Florida- Site Number : 8400147
RECRUITINGAltamonte Springs, Florida, 32714, United States
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North Central Neurology Associates- Site Number : 8401100
RECRUITINGCullman, Alabama, 35058, United States
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North Texas Institute of Neurology & Headache - Plano- Site Number : 8400082
RECRUITINGPlano, Texas, 75024, United States
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North Texas Institute of Neurology & Headache - Plano- Site Number : 8400083
RECRUITINGPlano, Texas, 75024, United States
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Palm Beach Neurology- Site Number : 8400105
RECRUITINGWest Palm Beach, Florida, 33407, United States
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Perseverance Research Center- Site Number : 8400138
RECRUITINGScottsdale, Arizona, 85253, United States
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Piedmont HealthCare - Lake Norman Neurology- Site Number : 8400002
RECRUITINGCharlotte, North Carolina, 28210, United States
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Private Practice - Dr. Regina Berkovich- Site Number : 8400005
RECRUITINGWest Hollywood, California, 90048, United States
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Raleigh Neurology Associates- Site Number : 8400014
RECRUITINGRaleigh, North Carolina, 27607, United States
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The Boster Center for Multiple Sclerosis- Site Number : 8400006
RECRUITINGColumbus, Ohio, 43235, United States
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The Ohio State University- Site Number : 8400009
RECRUITINGColumbus, Ohio, 43210, United States