Can a new score catch severe pregnancy sickness that others miss?
NCT ID NCT07767071
First seen Aug 17, 2026 · Last updated Aug 17, 2026
Summary
This study evaluates whether a French version of the HELP score can more accurately diagnose hyperemesis gravidarum (HG), a severe form of nausea and vomiting in pregnancy, compared to the standard PUQE score. Researchers will enroll 300 pregnant women experiencing nausea or vomiting in their first trimester and compare the diagnostic accuracy of both tools. The HELP score includes questions about hydration, diet, treatment effectiveness, and quality of life, which may better capture the full impact of HG. The goal is to see if this tool can better identify women who need medical intervention.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- HELP score questionnaire
- What this could lead to
- If validated, the French HELP scale could give doctors a more accurate tool to spot severe hyperemesis gravidarum, leading to earlier and better care for affected pregnancies.
- What could go wrong
- This is a validation study, not a treatment trial, so it won't directly improve outcomes. The scale may not prove more accurate than existing tools, and results may not apply beyond the French-speaking population studied.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CH de Béziers
Béziers, France
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CH de Mende
Mende, France
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CH de Sète
Sète, France
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CHU de Montpellier
Montpellier, France
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CHU de Nîmes
Nîmes, 30029, France
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CHU de Toulouse
Toulouse, France
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Centre Hospitalier Alès-Cévennes
Alès, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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