Metformin may stop severe pregnancy sickness before it starts

NCT ID NCT07129473

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether taking metformin-XR (a diabetes drug) daily before pregnancy can lower the risk and severity of Hyperemesis Gravidarum (HG)—extreme nausea and vomiting in pregnancy—in women aged 18-49 who had HG before and are trying to conceive. Participants either take the drug or join a survey-only group. Researchers will track side effects, HG recurrence, pregnancy outcomes, and newborn health.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Morning Sickness Nausea Vomiting hyperemesis gravidarum prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-••••

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