Childhood cancer survivors show signs of premature aging

NCT ID NCT02256137

Ongoing Knowledge-focused Sponsor: St. Jude Children's Research Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows over 1,500 young adult survivors of childhood cancers like leukemia, brain tumors, and Hodgkin lymphoma to see how frailty—a measure of physical weakness and vulnerability—changes over five years. Researchers want to know if frailty can predict future chronic health problems. The goal is to find early warning signs so doctors can step in sooner to help survivors stay healthier longer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors identify childhood cancer survivors at highest risk for early aging and chronic disease, leading to earlier interventions.
What could go wrong: This is an observational study, not a treatment trial. It measures frailty but does not test any intervention, so it cannot directly improve health.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute lymphoblastic leukemia brain cancer brain neoplasm Hodgkins lymphoma neoplasm Precursor Cell Lymphoblastic Leukemia-Lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE LYMPHOBLASTIC LEUKEMIA BRAIN TUMOR HODGKIN LYMPHOMA

Contacts and locations

Locations

St. Jude Children's Research Hospital

Memphis, Tennessee, 38105, United States

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