Sound waves could blast away artery blockages without surgery

NCT ID NCT05858905

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This study tests a new device that uses sound waves (lithotripsy) to break up hard calcium deposits in leg arteries, a condition called peripheral artery disease. About 75 adults with moderate to severe symptoms will receive the treatment. The goal is to see if the device safely opens the arteries enough to restore blood flow.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a device that uses sound waves (lithotripsy) to break up calcium deposits in leg arteries
What this could lead to
If successful, this could offer a safer, more effective way to open hardened leg arteries without major surgery.
What could go wrong
This is an early-stage study with only 75 participants, so results may not apply to everyone. Risks include artery damage or blockages.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Advanced Heart and Vein Center

    Thornton, Colorado, 80023, United States

  • Ascension Columbia St. Mary's

    Milwaukee, Wisconsin, 53211, United States

  • Ascension St. John Jane Phillips Hosptial

    Bartlesville, Oklahoma, 74006, United States

  • Cardiovascular Medicine PC

    Davenport, Iowa, 52803, United States

  • Charlotte Radiology

    Charlotte, North Carolina, 28202, United States

  • HCA Florida Blake Hospital

    Bradenton, Florida, 34209, United States

  • Lankenau Institute for Medical Research

    Bryn Mawr, Pennsylvania, 19096, United States

  • Marshfield Medical Center

    Marshfield, Wisconsin, 54449, United States

  • MedStar Montgomery Medical Center

    Olney, Maryland, 20832, United States

  • NYU Langone Health

    New York, New York, 10016, United States

  • North Mississippi Medical Center

    Tupelo, Mississippi, 38801, United States

  • Sentara Vascular Specialists

    Norfolk, Virginia, 23507, United States

  • Southcoast Hospitals Group

    New Bedford, Massachusetts, 02740, United States

  • Stanford Hospital and Clinics (SHC)

    Palo Alto, California, 94304, United States

  • Tallahassee Memorial Healthcare, Inc.

    Tallahassee, Florida, 32308, United States

  • The Heart Hospital Baylor

    Plano, Texas, 75093, United States

  • The Lindner Research Center at The Christ Hospital

    Cincinnati, Ohio, 45219, United States

  • The Miriam Hospital

    Providence, Rhode Island, 02906, United States

  • UnityPoint Health Trinity Bettendorf Hospital

    Bettendorf, Iowa, 52722, United States

  • University of Texas Southwestern Medical Center

    Dallas, Texas, 75390, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37212, United States

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