Sound waves could blast away artery blockages without surgery
NCT ID NCT05858905
First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time
Summary
This study tests a new device that uses sound waves (lithotripsy) to break up hard calcium deposits in leg arteries, a condition called peripheral artery disease. About 75 adults with moderate to severe symptoms will receive the treatment. The goal is to see if the device safely opens the arteries enough to restore blood flow.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a device that uses sound waves (lithotripsy) to break up calcium deposits in leg arteries
- What this could lead to
- If successful, this could offer a safer, more effective way to open hardened leg arteries without major surgery.
- What could go wrong
- This is an early-stage study with only 75 participants, so results may not apply to everyone. Risks include artery damage or blockages.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Advanced Heart and Vein Center
Thornton, Colorado, 80023, United States
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Ascension Columbia St. Mary's
Milwaukee, Wisconsin, 53211, United States
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Ascension St. John Jane Phillips Hosptial
Bartlesville, Oklahoma, 74006, United States
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Cardiovascular Medicine PC
Davenport, Iowa, 52803, United States
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Charlotte Radiology
Charlotte, North Carolina, 28202, United States
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HCA Florida Blake Hospital
Bradenton, Florida, 34209, United States
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Lankenau Institute for Medical Research
Bryn Mawr, Pennsylvania, 19096, United States
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Marshfield Medical Center
Marshfield, Wisconsin, 54449, United States
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MedStar Montgomery Medical Center
Olney, Maryland, 20832, United States
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NYU Langone Health
New York, New York, 10016, United States
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North Mississippi Medical Center
Tupelo, Mississippi, 38801, United States
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Sentara Vascular Specialists
Norfolk, Virginia, 23507, United States
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Southcoast Hospitals Group
New Bedford, Massachusetts, 02740, United States
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Stanford Hospital and Clinics (SHC)
Palo Alto, California, 94304, United States
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Tallahassee Memorial Healthcare, Inc.
Tallahassee, Florida, 32308, United States
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The Heart Hospital Baylor
Plano, Texas, 75093, United States
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The Lindner Research Center at The Christ Hospital
Cincinnati, Ohio, 45219, United States
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The Miriam Hospital
Providence, Rhode Island, 02906, United States
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UnityPoint Health Trinity Bettendorf Hospital
Bettendorf, Iowa, 52722, United States
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University of Texas Southwestern Medical Center
Dallas, Texas, 75390, United States
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Vanderbilt University Medical Center
Nashville, Tennessee, 37212, United States
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