New foot rehab aims to stop ankle sprains from coming back

NCT ID NCT04493645

Ongoing Disease control Sponsor: Matthew Hoch Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares a standard rehab program to a foot-intensive rehab (FIRE) program in 150 adults aged 18-44 with chronic ankle instability. Participants do 2 supervised and 3 home sessions per week for 6 weeks. The goal is to see if FIRE reduces re-injury rates, improves stability, and lessens symptoms better than standard care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: foot-intensive rehabilitation (FIRE) program
What this could lead to: If successful, this could provide a more effective rehab approach to reduce ankle sprains and improve stability in people with chronic ankle instability.
What could go wrong: This is a mid-sized trial comparing two rehab programs, so results may not apply to everyone. The intervention requires significant commitment (2 supervised and 3 home sessions per week for 6 weeks).

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ANKLE INJURIES are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

ankle injury injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANKLE INJURIES ANKLE SPRAINS

Contacts and locations

Show contact details

Locations

University of Kentucky

Lexington, Kentucky, 40536-0200, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.